Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5826209 | Current Opinion in Pharmacology | 2012 | 8 Pages |
Abstract
⺠Actin and myosin filaments are paradigmatic examples of sarcomeric drug targets. ⺠Sarcomeric protein kinases control muscle growth and turnover. ⺠The sarcomere-associated protein turnover machinery is important in muscle atrophy. ⺠Sarcomeric proteins emerge as useful drug targets in heart and skeletal muscle.
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Authors
Ay Lin Kho, Sue Perera, Alexander Alexandrovich, Mathias Gautel,