Article ID Journal Published Year Pages File Type
5826209 Current Opinion in Pharmacology 2012 8 Pages PDF
Abstract
► Actin and myosin filaments are paradigmatic examples of sarcomeric drug targets. ► Sarcomeric protein kinases control muscle growth and turnover. ► The sarcomere-associated protein turnover machinery is important in muscle atrophy. ► Sarcomeric proteins emerge as useful drug targets in heart and skeletal muscle.
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