Article ID Journal Published Year Pages File Type
5826295 Current Opinion in Pharmacology 2013 9 Pages PDF
Abstract
► First oral kinase inhibitor drug approved by FDA for rheumatoid disease. ► Intense activity to expand the utility of JAK inhibitors in other auto-immune indications. ► Focus is on discovering inhibitors of the JAK family with different and more selective profiles. ► Progress is also being made with orally active Syk inhibitors. ► Last two to three years have been transformative for kinase inhibitors in auto-immune diseases.
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