| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5826321 | Current Opinion in Pharmacology | 2012 | 9 Pages |
Abstract
⺠TRPV1 is activated/sensitized by multiple signals during inflammatory processes. ⺠TRPV1 phosphorylation reduces its threshold for detecting painful stimuli. ⺠TRPV1 ligands may alleviate pain at peripheral, spinal and supraspinal level. ⺠TRPV1 expression in the PAG is a source for inducing antinociception.
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Authors
Enza Palazzo, Livio Luongo, Vito de Novellis, Francesco Rossi, Ida Marabese, Sabatino Maione,