| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5826325 | Current Opinion in Pharmacology | 2012 | 7 Pages |
Abstract
⺠Nociception can be regulated at the level of local mRNA translation in nociceptors. ⺠Local mRNA translation can occur in primary afferents under the control of mTOR and ERK pathways. ⺠mTOR and ERK pathway inhibitors can reduce pain behavior. ⺠mTOR and ERK pathways may act independently, depending on the type of sensory afferents.
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Authors
Ilona Obara, Sandrine M Géranton, Stephen P Hunt,