Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5826366 | Current Opinion in Pharmacology | 2013 | 9 Pages |
Abstract
⺠The third generation β-blockers may act in a NO-dependent manner. ⺠They activate NOS synthases and/or prevent NO synthase uncoupling. ⺠They preserve NO bioavailability due to their antioxidant properties. ⺠This leads to vasodilatation, anti-proliferation and cardioprotection. ⺠These properties confer distinct advantages for treating cardiovascular disease.
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Authors
Paul M Vanhoutte, Yuansheng Gao,