Article ID Journal Published Year Pages File Type
5826371 Current Opinion in Pharmacology 2013 7 Pages PDF
Abstract
► Aldosterone levels predict mortality and/or MACCE in patients with CAD, MI or CHF. ► MR activation induces cardiovascular inflammation, endothelial dysfunction and remodelling. ► MRAs reduce mortality and hospitalization in patients with reduced LV function, CHF or acute MI. ► MRAs are still under-prescribed although prescription is safe under certain precautions.
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