| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5826428 | Current Opinion in Pharmacology | 2012 | 6 Pages |
Abstract
⺠The upregulation of NADPH oxidase (NOX) expression has been implicated in the aetiology of vein graft failure. ⺠Superoxide released from NOX augments neointima formation and inflammation that leads to pathology. ⺠A number of major drug classes inhibit the expression and activity of NOX. ⺠NOX and vein graft failure are discussed in this review with particular reference to nitric oxide and eicosanoids.
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Authors
Helen Weaver, Nilima Shukla, David Ellinsworth, Jamie Y Jeremy,