| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5826812 | European Journal of Pharmacology | 2016 | 9 Pages |
Abstract
Acute and long-term administration of RP3128 resulted in significant bronchodilation. Long-term administration of RP3128 exceeded the bronchodilatory effect of salbutamol and significantly decreased eNO and cytokine levels in plasma and BALF, which together with histological and immunohistochemical analysis validated its anti-inflammatory effect compared to budesonide. Data demonstrate the therapeutic potential of RP3128 in respiratory diseases causally associated with allergic inflammation.
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Authors
Martina Sutovska, Michaela Kocmalova, Sona Franova, Swaroop Vakkalanka, Srikant Viswanadha,