Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5827285 | European Journal of Pharmacology | 2015 | 9 Pages |
Abstract
In this review we will focus on Parkinson׳s disease and on the impact of a body of data issued from NHP studies. We will attempt to critically examine the advantages and limitations of various approaches from the perspective of the animal model used to address specific questions.
Keywords
UPDRSNRTNPositon emission tomographyGCH1GTP cyclohydrolase 1l-aromatic amino acid decarboxylaseVMAT2EIAVHLA-DRBH4NHP6OHDAIBA1AAV5HTGDNFAADCMPTP6-HydroxydopamineGAD1-methyl-4-phenyl-1,2,3,6-tetrahydropyridineglutamic acid decarboxylasel-DOPASNpcAChEFunctional assessmentAcetylcholineMRIViral vectorsParkinson׳s diseaseMagnetic resonance imagingsubstantia nigra pars compactatyrosine hydroxylaseSerotoninTranslational neuroscienceionized calcium-binding adapter molecule 1noradrenalineneurturinEquine infectious anemia virusAdeno-associated virusesPETCell transplantationGABAgamma-amino butyric acidgastro-intestinal
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Authors
Romina Aron Badin, Marta Vadori, Emanuele Cozzi, Philippe Hantraye,