SPA0355 suppresses T-cell responses and reduces airway inflammation in mice

Article ID	Journal	Published Year	Pages	File Type
5827727	European Journal of Pharmacology	2014	10 Pages	PDF

Keywords

OVA IKK GADPH MCH phorbol 12-myristate 13-acetate CFSE ZAP70 Th1 BAL Th2 ERK c-jun amino-terminal kinase TCr NFAT Jnk AHR PI3K NF-κB IκB kinase JAK/STAT PMA T-box expressed in T cells Allergic airway inflammation Ovalbumin CSA interferon IFN interleukin BALF regulated on activation, normal T cell expressed and secreted T-bet cluster of differentiation LAT Th2 cytokine Cyclosporine A BAL fluid Nuclear Factor of Activated T Cells nuclear factor-κB phosphoinositide 3-kinase bronchoalveolar lavage Methacholine RANTES T-cell response Airway hyperresponsiveness mitogen-activated protein kinase janus kinase/signal transducer and activator of transcription carboxyfluorescein succinimidyl ester MAP kinase extracellular signal-regulated kinase glyceraldehyde-3-phosphate dehydrogenase T-cell receptor

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SPA0355 suppresses T-cell responses and reduces airway inflammation in mice

Authors

Hyun-Young Jang, Raok Jeon, Kyung-Won Kang, Mi-Young Song, Jung Min Lim, Eun Lee, Jae-Ha Ryu, Sang-Myeong Lee, Byung-Hyun Park,