Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5831970 | International Immunopharmacology | 2016 | 8 Pages |
Abstract
IDO overexpression in DCs suppressed T cells alloresponses in vitro, and IDO+ DCs attenuated acute allograft rejection in vivo. Regulation of tryptophan catabolism by means of IDO overexpression in DCs may be a useful approach in cardiac transplantation and immunological tolerance.
Keywords
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Immunology
Authors
Chuan Li, Tong Liu, Na Zhao, Liwei Zhu, Pengzhi Wang, Xiangchen Dai,