Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5832611 | International Immunopharmacology | 2014 | 5 Pages |
Abstract
Inflammation was associated with the development of delayed gastric emptying, and blockade of p38 MAPK pathway with SB203580 ameliorates delayed gastric emptying in diabetic rats, at least in part, by inhibiting the expression of iNOS, TNF-a and IL-1β. Therefore, p38MAPK may serve as a novel target for the therapy of diabetes-related gastrointestinal dysmotility.
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Authors
Kun Yang, Bo Yun Qiu, Jing Yan, Ying Xue Yang, Tao Zhang, Xi Chen, Yu Pei Zou, Hua Tian Gan, Xiao Li Huang,