Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5833053 | International Immunopharmacology | 2013 | 8 Pages |
Abstract
⺠Zizyphus lotus polyphenols (ZLP) modulate Jurkat cell activation at the molecular level. ⺠The ZLP altered increases in [Ca2 +]i, evoked by thapsigargin. ⺠The ZLP also induced a decrease in the intracellular pH in Jurkat cells. ⺠The ZLP blocked T-cell cycle progression and decreased MAP kinase phosphorylation.
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Authors
Souleymane Abdoul-Azize, Malika Bendahmane, Aziz Hichami, Gado Dramane, Anne-Marie Simonin, Chahid Benammar, Hassimi Sadou, Simon Akpona, Es-Saddik El Boustani, Naim A. Khan,