| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5833305 | International Immunopharmacology | 2013 | 7 Pages |
Abstract
⺠The work evaluated the in vitro anti-allergic activity of pyridovericin (pyr). ⺠Pyr inhibited FcεRI-dependent and -independent degranulation of RBL-2H3 mast cells. ⺠Pyr impaired antigen-stimulated secretion of interleukin-4. ⺠Inhibition of stimulated Ca2 + accounts for the mechanism of action of pyr. ⺠Pyr is a promising prototype for the development of new anti-allergic drugs.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Marcela de Souza Santos, Willian Jonis Andrioli, Maria Perpétua Freire de Morais Del Lama, Jairo Kenupp Bastos, N.P. Dhammika Nanayakkara, Rose Mary Zumstein Georgetto Naal,