| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5833521 | International Immunopharmacology | 2012 | 7 Pages |
Abstract
⺠Azithromycin (AZM) shows anti-inflammatory activity aside from its antimicrobial effect. ⺠We examined the effect of AZM on natural killer (NK) cell function. ⺠AZM suppress CD69 expression and K562 cytotoxicity of IL-15-activated NK cells. ⺠AZM also inhibit IFN-gamma and TNF-alpha production of NK-92 and IL-15 activated NK cells. ⺠We demonstrate a new immunomodulatory effect of AZM to down-regulate NK response.
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Authors
Syh-Jae Lin, Dah-Chin Yan, Wen-I. Lee, Ming-Ling Kuo, Hsiu-Shan Hsiao, Pei-Yzu Lee,