| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5833523 | International Immunopharmacology | 2012 | 5 Pages |
Abstract
⺠Nitazoxanide suppresses the production of IL-6 from LPS-stimulated macrophages. ⺠Nitazoxanide inhibits the LPS-induced expression of IL-6 mRNA in RAW 264.7 cells. ⺠Orally administered nitazoxanide suppresses the increase in IL-6 levels in the blood of thioglycollate-injected mice. ⺠Nitazoxanide could be a promising lead compound for agents against various diseases associated with overproduction of IL-6.
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Authors
Seong Keun Hong, Hee Joo Kim, Chang Seon Song, In Soo Choi, Joong Bok Lee, Seung Yong Park,