Article ID Journal Published Year Pages File Type
5833527 International Immunopharmacology 2012 7 Pages PDF
Abstract
► Levels of serum MMP-1 and MMP-3 were decreased after T-614 therapy in RA patients. ► In vitro, T-614 inhibited the invasiveness of FLS. ► T-614 decreased expression of MMP-1 and MMP-3 in FLS both in mRNA and protein levels.
Keywords
Related Topics
Life Sciences Immunology and Microbiology Immunology
Preview
T-614 alters the production of matrix metalloproteinases (MMP-1 andMMP-3) and inhibits the migratory expansion of rheumatoid synovial fibroblasts, in vitro
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