Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5833544 | International Immunopharmacology | 2012 | 9 Pages |
Abstract
⺠We built a cell mode between inflammatory macrophages and colon cancer cells. ⺠TSA indirectly inhibits proliferation of colon cancer cells. ⺠The mechanism relies on TSA decreased production of inflammatory cytokines. ⺠TSA decreased miR-155 via repression of PU.1. ⺠TSA restores SHIP1, which is a negative regulator of inflammation.
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Authors
Jiajie Tu, Yingying Xing, Yongjian Guo, Feng Tang, Le Guo, Tao Xi,