Article ID Journal Published Year Pages File Type
5833544 International Immunopharmacology 2012 9 Pages PDF
Abstract
► We built a cell mode between inflammatory macrophages and colon cancer cells. ► TSA indirectly inhibits proliferation of colon cancer cells. ► The mechanism relies on TSA decreased production of inflammatory cytokines. ► TSA decreased miR-155 via repression of PU.1. ► TSA restores SHIP1, which is a negative regulator of inflammation.
Related Topics
Life Sciences Immunology and Microbiology Immunology
Authors
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