| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5833591 | International Immunopharmacology | 2012 | 13 Pages |
Abstract
⺠An ex vivo feeder-cell-free method was established for large-scale NK cell expansion. ⺠The expanded NK cells showed higher cytokine production in response to cancer cell. ⺠The expanded NK cells showed higher cytotoxicity against various cancer cells. ⺠The expanded NK cells showed synergistic cytotoxicity when combined with mAb drug. ⺠Cancer therapy by combination of expanded NK cells with mAb drugs is a useful tool.
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Authors
Xuewen Deng, Hiroshi Terunuma, Mie Nieda, Weihua Xiao, Andrew Nicol,