| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5833645 | International Immunopharmacology | 2012 | 9 Pages |
Abstract
⺠Trigonelline (TG) is a plant hormone which is claimed to have antidiabetic and hypoglycemic activities. ⺠Oxidative stress and apoptosis play a central role in diabetic nephropathy. ⺠TG treatment ameliorates oxidative stress in mononuclear cells. ⺠Decreased apoptosis in renal cells confirmed the antiapoptotic role of trigonelline. ⺠Renal histology showed decreased tubular damage and fibrosis after TG treatment.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Arvindkumar E. Ghule, Suresh S. Jadhav, Subhash L. Bodhankar,