| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5833648 | International Immunopharmacology | 2012 | 9 Pages |
Abstract
⺠We inhibited OGD-mediated microglial cell activation with baicalin. ⺠Baicalin inhibited OGD-mediated increases in cell viability and cytokine levels. ⺠Baicalin also attenuated the increase in the OGD-induced TLR4 mRNA. ⺠OGD-induced transfer of MyD88 from cytoplasm to membrane was attenuated. ⺠Baicalin may be developed for prevention of microglial damage in ischemic diseases.
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Authors
Jincai Hou, Jun Wang, Peng Zhang, Dan Li, Cuixiang Zhang, Haiping Zhao, Jianhua Fu, Bing Wang, Jianxun Liu,