Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5833666 | International Immunopharmacology | 2012 | 7 Pages |
Abstract
⺠Geniposide inhibited the LPS-induced TNF-α, IL-6 and IL-1β production. ⺠Geniposide blocked the phosphorylation of IkBα, p65, p38, ERK and JNK in cells. ⺠Geniposide inhibited TLR4 expression and IL-8 production in HEK293-mTLR4/MD-2 cells. ⺠Geniposide attenuated lung histopathologic changes in the mouse models.
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Authors
Yunhe Fu, Bo Liu, Jinhua Liu, Zhicheng Liu, Dejie Liang, Fengyang Li, Depeng Li, Yongguo Cao, Xichen Zhang, Naisheng Zhang, Zhengtao Yang,