Article ID Journal Published Year Pages File Type
5833666 International Immunopharmacology 2012 7 Pages PDF
Abstract
► Geniposide inhibited the LPS-induced TNF-α, IL-6 and IL-1β production. ► Geniposide blocked the phosphorylation of IkBα, p65, p38, ERK and JNK in cells. ► Geniposide inhibited TLR4 expression and IL-8 production in HEK293-mTLR4/MD-2 cells. ► Geniposide attenuated lung histopathologic changes in the mouse models.
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