Article ID Journal Published Year Pages File Type
5833680 International Immunopharmacology 2011 9 Pages PDF
Abstract
► The isoquinoline alkaloid berberine inhibits the growth two H1N1 strains of influenza A in several mammalian cell types. ► Berberine likely inhibits virus growth post-translationally, possibly through the inhibition of virus protein translocation. ► Berberine inhibits TNF-α and PGE2 production and this effect may be distinct from the effect on virus growth. ► Berberine-containing, ethanol extracts of goldenseal displayed activity as would be predicted from their berberine content.
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