Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5833691 | International Immunopharmacology | 2011 | 6 Pages |
Abstract
⺠We constructed a cell model for the over-expression of SR-AI in human 293T cells in vitro. ⺠Overexpression of SR-AI in 293T cells led to increased oxLDL uptake and binding. ⺠Overexpression of SR-AI in 293T cells leads to pro-atherogenic changes. ⺠Overexpression of SR-AI induced cell apoptosis by downregulation of Bcl-2 expression and upregulation of Bak-1 expression.
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Authors
Hong Yang, Shi-chao Chen, Yong-qing Tang, Ya-lei Dai,