Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5833757 | International Immunopharmacology | 2011 | 9 Pages |
Abstract
⺠We showed that Nrf2 is required for α-iso-cubebenol-mediated HO-1 expression. ⺠α-iso-cubebenol induced HO-1 expression through Nrf2, PI3K/Akt and ERK activation. ⺠α-iso-cubebenol has anti-inflammatory activity in P. gingivalis LPS signals. ⺠α-iso-cubebenol considered as a candidate in the treatment of periodontitis.
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Authors
Sun Young Park, Da Jung Park, Young Hun Kim, YoungHee Kim, Young-Whan Choi, Sang-Joon Lee,