| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5833813 | International Immunopharmacology | 2011 | 5 Pages |
Abstract
⺠Arctigenin activated the expression of p21 and p15 protein, and down-regulated the expression of cyclin D1, cyclin E, CDK4 and CDK2 ⺠Arctigenin inhibited hyper-phosphorylation of Rb protein ⺠Arctigenin induced cell cycle arrest from G1 to S ⺠Arctigenin activated Bax expression and down-regulated Bcl-2 expression ⺠Arctigenin induces apoptosis of SNN-1 and AGS cells by blocking hyper-phosphorylation of Rb via regulating the expression of cell cycle-related proteins.
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Authors
Jin Boo Jeong, Se Chul Hong, Hyung Jin Jeong, Jin Suk Koo,