| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5833817 | International Immunopharmacology | 2011 | 6 Pages |
Abstract
⺠TLR/MyD88 signaling pathway is responsible in IS2 β-glucan-mediated cellular response in RAW264.7 murine macrophages. ⺠IS2 β-glucan activates and leads to cytokine secretions of IL-6 and TNF-α in murine macrophages through TLR2 and TLR4. ⺠Phosphorylation of MAPKs and degradation of IκB-α was evident after stimulation with IS2 β-glucan.
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Authors
Hua Li, Wan-Jae Kim, Jun Jiang, Seung-Hwan Lee, Hyung-Sun Youn, Eun-Yi Moon, Tack-Joong Kim, Sang-Kyu Ye, Ji-Hwan Ryu, Tae-Bong Kang, Sushruta Koppula, Pyo-Jam Park, Dong-Kug Choi, Kwang-Ho Lee,