| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5833853 | International Immunopharmacology | 2011 | 6 Pages |
Abstract
⺠We define the abilities of CD4 T-cell subsets to induce the expression of CD154. ⺠Expression of CD154 was induced in 40-60% of total, and FoxP3â effector, CD4 T cells. ⺠The percentage of CD154 expression among CD4 FoxP3+ Treg cells was up to only ~ 8-9%. ⺠CD154 induction by CD4 FoxP3+ Treg cells is regulated by cell-intrinsic mechanisms. ⺠Differential CD154 induction may play a key role to distinguish CD4 subset functions.
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Authors
Wen Li, Timothy L. Carlson, William R. Green,