| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5833898 | International Immunopharmacology | 2011 | 10 Pages |
Abstract
⺠Up-regulation of mdr-1, mdr-3 and P-gp during DC development. ⺠Increased mdr-1 gene expression during DC maturation, but not mdr-3. ⺠Venlafaxine suppresses P-gp levels during DC maturation, but not mdr-1 gene. ⺠P-gp suppressor inhibits DC maturation and activation through IL-12 production. ⺠P-gp of DC is required for DC-mediated Th1/2 polarization and proliferation.
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Authors
Jun Sik Lee, In Duk Jung, Chang-Min Lee, Kyung Tae Noh, Jin Wook Park, Kwang Hee Son, Deok Rim Heo, Yong Kyoo Shin, Daejin Kim, Yeong-Min Park,