Article ID Journal Published Year Pages File Type
5834109 International Immunopharmacology 2012 7 Pages PDF
Abstract
► Sauchinone suppressed LPS-induced inflammatory responses in BV2 cells. ► Sauchinone inhibited the NF-kB activation induced by LPS treatment in BV2 cells. ► Sauchinone did block the Akt phosphorylation but not MAPK activation in BV2 cells treated with LPS. ► The inhibitory effect of sauchinone on LPS-induced inflammatory responses is mediated through Akt and NF-kB signaling pathway.
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