Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5834109 | International Immunopharmacology | 2012 | 7 Pages |
Abstract
⺠Sauchinone suppressed LPS-induced inflammatory responses in BV2 cells. ⺠Sauchinone inhibited the NF-kB activation induced by LPS treatment in BV2 cells. ⺠Sauchinone did block the Akt phosphorylation but not MAPK activation in BV2 cells treated with LPS. ⺠The inhibitory effect of sauchinone on LPS-induced inflammatory responses is mediated through Akt and NF-kB signaling pathway.
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Authors
Eun Young Jang, Chae Ha Yang, Min Ho Han, Yung Hyun Choi, Meeyul Hwang,