Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5834216 | International Immunopharmacology | 2011 | 6 Pages |
Abstract
⺠Levels of LXRs expression were decreased in the lung tissues of rats with ALI. ⺠Activation of LXRs by the synthetic agonist T0901317 ameliorates lung histopathologic damage. ⺠T0901317 also suppresses lung inflammatory responses and inhibits neutrophil transmigration. ⺠This is linked to inhibiting NF-κB activation and decreasing ICAM-1gene expression.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Deming Wang, Meimei Liu, Yongsheng Wang, Min Luo, Jiazheng Wang, Changzong Dai, Ping Yan, Xiongjun Zhang, Yan Wang, Chaoke Tang, Ji Xiao,