| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5834229 | International Immunopharmacology | 2011 | 6 Pages |
Abstract
⺠Introducing 15-p-Chlorobenzylidene significantly enhances anti-inflammatory effect. ⺠Compound 6, the most potent one, inhibits ear edema by 79.4% at 1.35 mmol/kg (ig). ⺠Improved activity (6) is owing to inhibition of iNOS activity and NO production. ⺠Compound 5 exerts the enhanced activity through inhibition of PGE2 production.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Gui-Fu Dai, Jin Zhao, Zhi-Wen Jiang, Li-Ping Zhu, Hai-Wei Xu, Wen-Yan Ma, Xiao-Rang Chen, Rui-Jing Dong, Wei-Yi Li, Hong-Min Liu,