Article ID Journal Published Year Pages File Type
5834234 International Immunopharmacology 2011 9 Pages PDF
Abstract
► As one of main bioactive substances dissociated from chicken bile, TCDCA confered good anti-adjuvant arthritis activity. ► TCDCA suppressed synoviocytes proliferation from adjuvant arthritis rat in a concentration ranging from 0 µg/mL to 1000 µg/mL. ► TCDCA showed inhibition of the protein and mRNA expression of TNF-α, IL-1β and IL-6, and augment of IL-10.
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