Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5841334 | Life Sciences | 2016 | 4 Pages |
Abstract
ET-1-mediated elevation of intracellular Ca2Â + is strongly linked to renal microvascular contraction and is crucial for ET-1-induced contraction of SMC. The two-photon imaging of intracellular Ca2Â + in intact SMC of rat renal resistance arteries is a powerful technique which allows the detailed ex vivo analysis of intracellular Ca2Â + handling by ET-1, an important player in hypertension-related kidney diseases.
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Authors
Oleg Palygin, Bradley Miller, Daria V. Ilatovskaya, Andrey Sorokin, Alexander Staruschenko,