| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5841449 | Life Sciences | 2016 | 14 Pages |
Abstract
The present study demonstrates that atherosclerotic plaque constituents enhance macrophage cellular oxidative stress, and accumulation of cholesterol and triglycerides, as shown in both in vivo and in vitro model systems.
Keywords
hLLEAtherosclerotic lesion4-HNEFITCPON2DGAT1HDLDGATMPMPON1HMGCRDCFH2′,7′-dichlorofluorescin diacetateApoE−/− micehigh-density lipoproteinHMG-CoA reductaseROSOxidative stressLow-density lipoproteinLDLMacrophagesMouse peritoneal macrophagesTriglyceride metabolismCholesterol metabolismMaleParaoxonase 1Paraoxonase 2GlucoseReactive oxygen species
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Authors
Niroz Abu-Saleh, Michael Aviram, Tony Hayek,