| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5841450 | Life Sciences | 2016 | 9 Pages |
Abstract
Our data suggests that combination of telmisartan with 5-FU treatment is beneficial in controlling cancer cachexia. Telmisartan can be used as an add-on therapy with 5-FU or other traditional chemotherapeutic agents.
Keywords
NF-κBRAASMNNGQOLPPARγPKCGSHHIF-1NADPHGLUT1EDLVSMCHDLDBPVLDL5-FUGGTSBPIL-6MDAQuality of life5-flourouracilN-methyl-N′-nitro-N-nitrosoguanidineROSTibialis AnteriorMuscle atrophyDyslipidemiainterleukin-6triglyceridetumor necrosis factor-alphaSODVascular smooth muscle cellSuperoxide dismutaseRenin Angiotensin Aldosterone SystemHypoxia Inducible FactorTNF-αnuclear factor kappa Bdiastolic blood pressuresystolic blood pressureLDHhigh density lipoproteinvery low density lipoproteinlow density lipoproteinLDLmalondialdehydeHyperglycemiaC-reactive proteinCRPProtein kinase Creduced glutathionegamma glutamyltransferaseglucose transporter-1Reactive oxygen speciesPeroxisome proliferator activated receptor gamma
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Authors
Shreesha Sukumaran, Hetal J. Patel, Bhoomika M. Patel,