Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5841512 | Life Sciences | 2016 | 23 Pages |
Abstract
These results demonstrate that IL-10 counteracts both the pressoric activity of Ang II as well as vascular dysfunction associated with hypertension, partially, modulating the RhoA-Rho kinase pathway. Strategies to enhance IL-10 levels during hypertension may enhance the benefits provided by regular treatments.
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Authors
Victor V. Lima, Saiprasad M. Zemse, Chin-Wei Chiao, Gisele F. Bomfim, Rita C. Tostes, R. Clinton Webb, Fernanda R. Giachini,