Article ID Journal Published Year Pages File Type
5841516 Life Sciences 2016 5 Pages PDF
Abstract
This study provided pharmacological evidence that tapentadol inhibits stimulated CGRP release from the rat brainstem in vitro through a mechanism involving an increase in 5-HT levels in the system and the subsequent activation of 5-HT3 receptors.
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Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine
Preview
The analgesic agent tapentadol inhibits calcitonin gene-related peptide release from isolated rat brainstem via a serotonergic mechanism
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