Protective effect of sulfurous water in peripheral blood mononuclear cells of Alzheimer's disease patients

Article ID	Journal	Published Year	Pages	File Type
5841686	Life Sciences	2015	7 Pages	PDF

Abstract

The protective effect of SW was proved for the first time not only in DNA stability but also in cell viability preservation in AD, indicating that further research in other in vitro and in vivo models could lead to include SW as a possible therapy for AD.

Keywords

RPMI-1640 GSH NAC NaCl N-acetyl-l-cysteine LSD NaOH PBMCs Hcy CASP PBS hOGG1 TRIS 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide DMSO DNA MTT ROS Hydrogen peroxide Oxidative DNA damage EDTA ethylene diamine tetraacetic acid deoxyribonucleic acid Alzheimer's disease analysis of variance ANOVA Trolox Triton X-100 Oxidative stress least significant difference standard error of the mean dimethyl sulphoxide Comet assay Cell viability Sodium chloride peripheral blood mononuclear cells Hydrogen sulfide Phosphate buffered saline SEM Roswell Park Memorial Institute medium homocysteine sodium hydroxide CO2 Glutathione Reactive oxygen species