Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5841700 | Life Sciences | 2015 | 6 Pages |
Abstract
BDNF hyperactivity was also found in several studies of autistic patients. Together with our previous studies, our model of prenatal LPS induced autistic-like behavioral, brain, and immune disturbances. This suggests that it is a valid rat model of autism. Prenatal zinc prevented reproductive, communication, and BDNF impairments. The present study revealed a potential beneficial effect of prenatal zinc administration for the prevention of autism with regard to the BDNF pathway.
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Authors
Thiago B. Kirsten, Nicolle Queiroz-Hazarbassanov, Maria M. Bernardi, Luciano F. Felicio,