Article ID Journal Published Year Pages File Type
5841715 Life Sciences 2015 9 Pages PDF
Abstract
Graphical representation of mechanism of action of Telmisartan (TS): Makes possible link between TLR4 signalling by PPARγ activation and attenuated the LPS inflammatory mediated intoxication in the IMR-32 neuronal cell line via SARM activation, which results in attenuation of phosphorylation on p38, ERK and JNK and p65(NFkB) and pro-inflammatory cytokines.144
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Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine
Preview
Telmisartan attenuated LPS-induced neuroinflammation in human IMR-32 neuronal cell line via SARM in AT1R independent mechanism
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