Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5842039 | Life Sciences | 2013 | 7 Pages |
Abstract
Pitavastatin appeared to inhibit TGF-β1-induced fibrogenic mediator production from lung fibroblasts via the mevalonic cascade. Although further evaluation of the signaling pathways for these phenomena is necessary, our results suggest the potential benefits of pitavastatin.
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Authors
Hiroaki Oka, Hiroshi Ishii, Atsuko Iwata, Hisako Kushima, Satoshi Toba, Kazuhiko Hashinaga, Kenji Umeki, Issei Tokimatsu, Kazufumi Hiramatsu, Jun-ichi Kadota,