Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5842041 | Life Sciences | 2013 | 8 Pages |
Abstract
Postoperative pain contributes to the development of memory deficits after anesthesia and surgery via up-regulation of hippocampal NMDA receptors. Our findings suggest that postoperative pain management may be important for the prevention of POCD in elderly patients.
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Authors
Haidong Chi, Takashi Kawano, Takahiko Tamura, Hideki Iwata, Yasuhiro Takahashi, Satoru Eguchi, Fumimoto Yamazaki, Naoko Kumagai, Masataka Yokoyama,