Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5842345 | Life Sciences | 2013 | 7 Pages |
Abstract
We suggested that the observed impairments in the F1 females were a consequence of a motivational change induced by prenatal LPS, as (1) no changes in motor activity were observed, (2) prenatal LPS-exposure was reported by our group to induce motivational impairments in males, and (3) the existence of a strong connection between striatal dopaminergic activity and motivation-oriented activities. The present findings strongly indicate a maternal effect for prenatal LPS, at least for the F1 generation.
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Ana M.S. Soto, Thiago B. Kirsten, Thiago M. Reis-Silva, Maria F.M. Martins, Elisabeth Teodorov, Jorge C. Flório, João Palermo-Neto, Maria M. Bernardi, Eduardo F. Bondan,