Article ID Journal Published Year Pages File Type
5842366 Life Sciences 2012 6 Pages PDF
Abstract
Haloperidol induced DUSP6 expression related to intronic demethylation and inhibited MIA PaCa-2 cell proliferation, which suggests demethylating activity and anti-cancer effects of haloperidol. These findings suggest the possible involvement of epigenetic regulatory mechanisms in the action mechanism of haloperidol.
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Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine
Preview
Haloperidol induces demethylation and expression of the dual specificity phosphatase 6 gene in MIA PaCa-2 human pancreatic cancer cells
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