| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5842510 | Life Sciences | 2012 | 4 Pages |
Abstract
In hemodialysis patients, plasma levels of the inactive precursors big ET-1, big ET-2, and big ET-3 levels are markedly increased, yet there is only a moderate increase in plasma levels of the active products, ET-1 and ET-3. This suggests that the activity of endothelin converting enzyme contributing to circulating levels of ET-1 and ET-3 may be decreased in patients on chronic hemodialysis.
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Authors
Yumi Miyauchi, Satoshi Sakai, Seiji Maeda, Nobutake Shimojo, Shigeyuki Watanabe, Satoshi Honma, Keisuke Kuga, Kazutaka Aonuma, Takashi Miyauchi,