Article ID Journal Published Year Pages File Type
5842732 Life Sciences 2011 7 Pages PDF
Abstract
This study suggests that downregulation of GATA-3 and c-Maf via the suppression of p38, IKK-β and IκB-α phosphorylation might contribute to the inhibitory effect of shikonin on mitogen-induced IL-4 and IL-5 production in EL-4T cells. Furthermore, shikonin is a potential drug for treating allergic diseases.
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Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine
Preview
Shikonin inhibited mitogen-activated IL-4 and IL-5 production on EL-4 cells through downregulation of GATA-3 and c-Maf induction
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