Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5842757 | Life Sciences | 2012 | 8 Pages |
Abstract
IGPS exerts a protective effect against renal injury in UAN rats, possesses anti-inflammatory and immunomodulatory effects by inactivating NF-κBp65 pathway transmembrane signal transduction, down regulating the expression of MCP-1 and α-SMA to modulate pro-inflammatory mediator production in nephropathy tissue to improve renal fibrosis in UAN rats.
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Authors
Wenjing Zhu, Mingqun Pang, Liuyi Dong, Xueying Huang, Shuangmiao Wang, Lanlan Zhou,