| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5842811 | Life Sciences | 2011 | 7 Pages |
Abstract
Hippocampal ischemia aggravates cognitive impairment of AD rats by increasing Aβ deposits, neuron loss and tau phosphorylation in hippocampus. The enhanced inflammatory response may be responsible for cerebral ischemia-induced aggravation of cognitive impairment in AD rats. Based on these findings, prevention and treatment of cerebral ischemia may improve clinical symptoms of AD and suppress the progression of AD.
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Authors
Jing Li, Yan-Jiang Wang, Meng Zhang, Chuan-Qin Fang, Hua-Dong Zhou,