Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5842864 | Life Sciences | 2012 | 7 Pages |
Abstract
The important implication of this study is the persistent abnormal fluctuation of neurotrophic factor expression for a prolonged period, triggered even after the brain growth spurt. Given that neurotrophic factors play important roles in brain development, it can be speculated that the altered expression of these factors induced by maternal separation may interrupt normal brain development and ultimately lead to functional disruption. However, the possibility of such changes leading to various functional disruptions and the underlying mechanisms involved require further study.
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Kyoung-Youl Lee, Takanori Miki, Toshifumi Yokoyama, Masaaki Ueki, Katsuhiko Warita, Shingo Suzuki, Ken-Ichi Ohta, Zhi-Yu Wang, Mostofa Jamal, Tomiko Yakura, Jun-Qian Liu, Naohisa Hosomi, Yoshiki Takeuchi,